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Myasthenia Gravis

  • Author: Dr. Hasan Altarrah
  • Published Date: 10/05/2026
  • Last Modified Date:
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  • Reviews: ( 0 Reviews )
  • Category :Internal Medicine
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Additional Information:

  • CC: fatigue or difficulty swallowing, or ptosis

Description

Differential Diagnosis
  • Stroke
  • Guillain barré syndrome
  • Multiple sclerosis
  • Lambert-Eaton myasthenic syndrome
Tests for Myasthenia Gravis
  • Anti-AChR antibodies
  • Anti-MuSK antibodies
  • Edrophonium (Tensilon) test
  • CT or MRI chest to look for thymoma
  • TFT to look for Graves’ disease
  • Ice test
  • EMG
  • FVC to assess respiratory muscle function
Management of Myasthenia Gravis

Acute

  • IVIG
  • Plasmapheresis

Chronic

  • Acetylcholine esterase inhibitor like pyridostigmine
  • Immunosuppression like steroids & azathioprine
  • Thymectomy
Remember
  • Worsening may occur with medications such as fluoroquinolones, aminoglycosides and magnesium
  • Immunosuppressive therapy should be maintained throughout pregnancy as it reduces neonatal muscle weakness and controls maternal myasthenia

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