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Case Details

Product
Product

Splenomegaly

  • Author: Dr. Hasan Altarrah
  • Published Date: 13/05/2026
  • Last Modified Date:
  • Rating :
  • Reviews: ( 0 Reviews )
  • Category :Internal Medicine
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Additional Information:

  • CC: fatigue

Description

Clinical Signs
  • Pallor
  • Jaundice
Area to Examine
  • Abdomen
  • Splenomegaly +/- hepatomegaly
  • Lymph nodes
Differential Diagnosis
  • Hemolytic anemia
  • Portal hypertension
  • CML
  • Myelofibrosis
  • Malaria
  • Hepatitis
  • Infective endocarditis
  • Visceral leishmaniasis
  • Amyloidosis
  • EBV
  • Myelo/lymphoproliferative disorders
What Will You Do?
  • Coombs test
  • Ultrasound abdomen
  • Bone marrow aspirate
  • CT chest & abdomen
  • Lymph node biopsy
  • Viral serology
  • Thin & thick blood film
  • Basic profile: CBC, LFT, blood film, reticulocytes, bilirubin, haptoglobin
Remember the Spleen
  • Has a notch
  • Enlarges inferiorly & medially

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