Splenomegaly
CC: fatigue
Clinical signs
Pallor
Jaundice
Splenomegaly +/- hepatomegaly
Area to examine?
Abdomen
Lymph nodes
Differential diagnosis:
Hemolytic anemia
Portal hypertension
CML
Melofibrosis
Malaria
Hepatitis
Infective endocarditis
Visceral leishmaniasis
Amyloidosis
Myelo/lymphoproliferative disorders
EBV
What will you do?
Basic profile like CBC, LFT, blood film, relics, bilirubin, haptoglobin, …
Coombs test U/S abdomen
CT chest & abdomen
Bone marrow aspirate
Lymph node biopsy
Viral serology
Thin & thick blood film
Remember the spleen:
Has a notch
Enlarges inferiorly & medially
